產(chǎn)品編號 | bs-1136R |
英文名稱 | Synaptotagmin-2 Rabbit pAb |
中文名稱 | 突觸結(jié)合蛋白相關(guān)基因2抗體 |
別 名 | Synaptotagmin 2; Synaptotagmin II; Synaptotagmin2; SynaptotagminII; SYT 2; Syt II; SytII.Synaptotagmin II; SYNII; Syt2; RATSYNII; SYNII; FLJ42519; KIAA4194; LOC100127887; mKIAA4194; R74640; RATSYNII; SYNAPTOTAGMIN 2; SYT2; SytII; SYT2_HUMAN. |
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Specific References (1) | bs-1136R has been referenced in 1 publications.
[IF=4.5] Shaoping Zhong. et al. GABAergic Interneuron and Neurotransmission Are mTOR-Dependently Disturbed in Experimental Focal Cortical Dysplasia. Mol Neurobiol. 2021 Jan;58(1):156-169 IHC ; Mouse.
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研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 46 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human synaptotagmin-2: 285-380/419 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM] Subunit: Homotetramer. Interacts with stonin 2. Interacts with SCAMP5. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Similarity: Belongs to the synaptotagmin family. Contains 2 C2 domains. SWISS: Q8N9I0 Gene ID: 127833 Database links: Entrez Gene: 127833 Human Entrez Gene: 20980 Mouse Omim: 600104 Human SwissProt: Q8N9I0 Human SwissProt: P46097 Mouse Unigene: 25422 Human Unigene: 5102 Mouse Unigene: 88574 Rat |
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