產(chǎn)品編號(hào) | bs-6009R |
英文名稱 | GAS8 Rabbit pAb |
中文名稱 | 生長(zhǎng)停滯特異性蛋白8抗體 |
別 名 | Growth arrest specific protein 8; GAS 11; GAS 8; GAS-8; GAS11; Growth arrest specific 11; Growth arrest specific 8; Growth arrest specific protein 11; Growth arrest specific protein 8; GAS8_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 56 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GAS8: 51-150/478 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Function: Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. Subunit: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum basal body. Golgi apparatus. Note=Associates with microtubules. Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa. Tissue Specificity: Expressed in the heart, skeletal muscle, pancreas and liver. Weakly or not expressed in brain, placenta, lung and kidney. Similarity: Belongs to the GAS8 family. SWISS: O95995 Gene ID: 2622 Database links: Entrez Gene: 2622 Human Entrez Gene: 104346 Mouse Omim: 605178 Human SwissProt: O95995 Human SwissProt: Q60779 Mouse Unigene: 431792 Human Unigene: 117265 Mouse Unigene: 209051 Rat
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