| 產(chǎn)品編號(hào) | bs-6306R |
| 英文名稱 | GCMA Rabbit pAb |
| 中文名稱 | 絨毛膜特異性轉(zhuǎn)錄因子GCMa抗體 |
| 別 名 | Chorion specific transcription factor GCMa; Chorion-specific transcription factor GCMa; GCM 1; GCM A; GCM motif protein 1; Gcm1; GCM1_HUMAN; Gcm1rs1; GCMA; Gcmrs2; Glial cells missing homolog 1; Glial cells missing homolog a; Glide; hGCMa. |
 |
Specific References (1) | bs-6306R has been referenced in 1 publications.
[IF=4.545] Zhe Li. et al. SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth. Biomed Pharmacother. 2021 Jan;133:111011 WB ; Mouse.
|
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 48 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GCMA/GCM1: 121-220/436 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008]. Function: Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Subcellular Location: Nucleus. Tissue Specificity: Placenta specific. Similarity: Contains 1 GCM DNA-binding domain. SWISS: Q9NP62 Gene ID: 8521 Database links: UniProtKB/Swiss-Prot: Q9NP62.1 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Rat Spleen tissue lysates
Lane 2: Rat Stomach tissue lysates
Primary: Anti-GCMA (bs-6306R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kDa
Observed band size: 50 kDa
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GCMA) Polyclonal Antibody, Unconjugated (bs-6306R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
|
