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C1RL Rabbit pAb (bs-15087R)  
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產品編號 bs-15087R
英文名稱 C1RL Rabbit pAb
中文名稱 補體C1RL鏈多肽抗體
別    名 C1r like protein; C1r like serine protease analog; C1r like serine protease analog protein; C1r LP; C1r-like protein; C1r-like serine protease analog protein; C1r-LP; C1rl; C1RL_HUMAN; C1RL1; C1RLP; CLSPa; complement C1r like proteinase; Complement C1r subcomponent-like protein; Complement component 1 r subcomponent like.  
研究領域 細胞生物  免疫學  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1RL: 101-200/487 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 No data available.

Function:
Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

Subcellular Location:
Secreted.

Tissue Specificity:
Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).

Similarity:
Belongs to the peptidase S1 family.
Contains 1 CUB domain.
Contains 1 peptidase S1 domain.

SWISS:
Q9NZP8

Gene ID:
51279

Database links:

Entrez Gene: 51279 Human

Omim: 608974 Human

SwissProt: Q9NZP8 Human

Unigene: 631730 Human



產品圖片
Sample: Liver(Mouse) Cell Lysate at 40 ug Primary: Anti-C1RL (bs-15087R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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