| 產(chǎn)品編號 | bs-14062R |
| 英文名稱 | CRLF3 Rabbit pAb |
| 中文名稱 | 細(xì)胞因子受體樣因子3抗體 |
| 別 名 | CREME 9; CREME9; CRLF 3; CRLM9; Cytokine receptor like factor 3; Cytokine receptor like molecule 9; Cytokine receptor related protein 4; CYTOR4; FRWS; MGC20661; P48; p48.2; Type I cytokine receptor like factor; Type I cytokine receptor like factor p48; CRLF3_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞周期蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CRLF3: 21-120/442 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012] Function: CRLF3 (Cytokine receptor-like factor 3) contains one fibronectin type-III domain. It is expressed in skin and squamous cell carcinoma (SCC) and in lesion actinic keratosis (AK). Subcellular Location: Cytoplasmic Tissue Specificity: Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK). Similarity: Belongs to the cytokine receptor-like factor 3 family. Contains 1 fibronectin type-III domain. SWISS: Q8IUI8 Gene ID: 51379 Database links: Entrez Gene: 51379 Human Entrez Gene: 54394 Mouse Omim: 614853 Human SwissProt: Q8IUI8 Human SwissProt: Q9Z2L7 Mouse Unigene: 649372 Human Unigene: 272093 Mouse |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CRLF3) Polyclonal Antibody, Unconjugated (bs-14062R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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