| 產(chǎn)品編號(hào) | bs-17145R |
| 英文名稱 | TRMT5 Rabbit pAb |
| 中文名稱 | TRMT5蛋白抗體 |
| 別 名 | KIAA1393; M1G methyltransferase; M1G-methyltransferase; TRM5; TRM5 tRNA methyltransferase 5 homolog(S. cerevisiae); TRMT5; TRMT5_HUMAN; tRNA(guanine-N(1)-)-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5; tRNA N1G37 methyltransferase. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 58 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRMT5: 201-300/509 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008] Function: Specifically methylates guanosine-37 in various tRNAs. Not dependent on the nature of the nucleoside 5' of the target nucleoside. Subunit: Monomer. Subcellular Location: Cytoplasm. Similarity: Belongs to the TRM5 / TYW2 family. SWISS: Q32P41 Gene ID: 57570 Database links: Entrez Gene: 57570 Human Entrez Gene: 76357 Mouse Omim: 611023 Human SwissProt: Q32P41 Human SwissProt: Q9D0C4 Mouse Unigene: 380159 Human Unigene: 311344 Mouse |
