產(chǎn)品編號(hào) | bs-19046R |
英文名稱 | NCCRP1 Rabbit pAb |
中文名稱 | 非特異性細(xì)胞毒性受體蛋白1抗體 |
別 名 | Gm163; FBXO50; LOC342897; NCCRP 1; NCCRP1; NCRP1_HUMAN; Non specific cytotoxic cell receptor protein 1 homolog(zebrafish); Non specific cytotoxic cell receptor protein 1 homolog; Non-specific cytotoxic cell receptor protein 1 homolog; Nonspecific cytotoxic cell receptor protein 1 homolog; RGD1305932v. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 31 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NCCRP1: 201-275/275 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
NCCRP1 is a 275 amino acid protein that contains one FBA (F-box associated) domain. The gene encoding NCCRP1 maps to human chromosome 19q13.2. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. Function: Promotes cell proliferation. Subcellular Location: Cytoplasm Tissue Specificity: Expressed in the esophagus, oral cavity, skin, tongue and reproductive organs. Similarity: Contains 1 FBA (F-box associated) domain. SWISS: Q6ZVX7 Gene ID: 342897 Database links: Entrez Gene: 342897 Human Entrez Gene: 233038 Mouse SwissProt: Q6ZVX7 Human Unigene: 726934 Human |
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