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PRRG1 Rabbit pAb (bs-19433R)  
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產品編號 bs-19433R
英文名稱 PRRG1 Rabbit pAb
中文名稱 跨膜γ羧基酸蛋白1抗體
別    名 PRGP1; Proline rich gamma carboxyglutamic acid protein 1; Proline rich Gla(G carboxyglutamic acid) 1; Proline rich Gla(G carboxyglutamic acid) polypeptide 1; Proline rich Gla protein 1; Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla protein 1; PRRG1; TMG1; TMG1_HUMAN; Transmembrane gamma carboxyglutamic acid protein 1 [Precursor]; Transmembrane gamma-carboxyglutamic acid protein 1.  
研究領域 腫瘤  細胞生物  免疫學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRRG1: 21-100/318 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in the spinal cord.

Post-translational modifications:
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.

Similarity:
Contains 1 Gla (gamma-carboxy-glutamate) domain.

SWISS:
O14668

Gene ID:
5638

Database links:

Entrez Gene: 785916 Cow

Entrez Gene: 5638 Human

Entrez Gene: 546336 Mouse

Entrez Gene: 363472 Rat

Omim: 604428 Human

SwissProt: A7Z070 Cow

SwissProt: O14668 Human

Unigene: 190341 Human



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