| 產(chǎn)品編號 | bs-20061R |
| 英文名稱 | phospho-FOXO6 (Ser184) Rabbit pAb |
| 中文名稱 | 磷酸化叉頭蛋白O6抗體 |
| 別 名 | Foxo6(phospho Ser184); Foxo6(phospho S184); Forkhead box protein O6; FOXO6_HUMAN. |
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Specific References (1) | bs-20061R has been referenced in 1 publications.
[IF=4.932] Yi Ren. et al. Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway. Int Immunopharmacol. 2021 Nov;100:108077 WB ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 51 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human FOXO6 around the phosphorylation site of Ser184: AV(p-S)MD |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons. Function: Transcriptional activator. Subcellular Location: Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors. Post-translational modifications: Phosphorylation of Ser-184 is be important in regulating the transacriptional activity. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: A8MYZ6 Gene ID: 100132074 Database links: Entrez Gene: 100132074 Human Entrez Gene: 329934 Mouse Omim: 611457 Human SwissProt: A8MYZ6 Human SwissProt: Q70KY4 Mouse Unigene: 277090 Mouse Unigene: 190858 Rat |
