產(chǎn)品編號 | bs-19660R |
英文名稱 | SerpinB8 Rabbit pAb |
中文名稱 | 絲氨酸蛋白酶抑制劑B8抗體 |
別 名 | CAP 2; CAP-2; CAP2; Cytoplasmic antiproteinase 2; OTTHUMP00000067000; OTTHUMP00000067001; Peptidase inhibitor 8; PI 8; PI-8; PI8; Protease inhibitor 8(ovalbumin type); Serine(or cysteine) proteinase inhibitor clade B(ovalbumin) member 8; Serpin B8; Serpin peptidase inhibitor clade B(ovalbumin) member 8; Serpinb8; SPB8_HUMAN. |
研究領域 | 細胞生物 免疫學 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,Cat,GuineaPig,Horse) |
產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 43 kDa |
檢測分子量 | |
細胞定位 | 細胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SerpinB8: 121-220/374 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).[supplied by OMIM, Jan 2010] Subcellular Location: Cytoplasm. Similarity: Belongs to the serpin family. Ov-serpin subfamily. SWISS: P50452 Gene ID: 5271 Database links: Entrez Gene: 5271 Human Entrez Gene: 20725 Mouse Omim: 601697 Human SwissProt: P50452 Human SwissProt: O08800 Mouse Unigene: 368077 Human Unigene: 83909 Mouse Unigene: 104823 Rat |
產(chǎn)品圖片 | |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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