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PPP3CC Rabbit pAb (bs-19973R)  
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產(chǎn)品編號 bs-19973R
英文名稱 PPP3CC Rabbit pAb
中文名稱 蛋白磷酸酶3調(diào)節(jié)亞基C抗體
別    名 calcineurin A gamma; CALCINEURIN A3; Calcineurin; Calcineurin testis specific catalytic subunit; Calmodulin dependent calcineurin A subunit gamma isoform; Calmodulin-dependent calcineurin A subunit gamma isoform; CALNA3; CAM PRP catalytic subunit; CAM-PRP  
Specific References  (1)     |     bs-19973R has been referenced in 1 publications.
[IF=3.509] Xin Shan. et al. Proteomic analysis of healthy and atretic porcine follicular granulosa cells. J Proteomics. 2021 Feb;232:104027  WB ;  Pig.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPP3CC: 51-150/512 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.

Subunit:
Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

Tissue Specificity:
Testis.

Similarity:
Belongs to the PPP phosphatase family. PP-2B subfamily.

SWISS:
P48454

Gene ID:
5533

Database links:

Entrez Gene: 5533 Human

Entrez Gene: 19057 Mouse

Entrez Gene: 171378 Rat

Omim: 114107 Human

SwissProt: P48454 Human

SwissProt: P48455 Mouse

Unigene: 728861 Human

Unigene: 731683 Human

Unigene: 439683 Mouse



產(chǎn)品圖片
Sample: Testis(Mouse)Lysate at 40 ug Primary: Anti-PPP3CC(bs-19973R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 58kD Observed band size: 58kD
Sample: Hela(Human) Cell Lysate at 40 ug Primary: Anti-PPP3CC (bs-19973R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
Sample: DU145(Human) Cell Lysate at 40 ug Primary: Anti-PPP3CC (bs-19973R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PPP3CC) Polyclonal Antibody, Unconjugated (bs-19973R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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