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PADI6 Rabbit pAb (bs-19703R)  
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產(chǎn)品編號 bs-19703R
英文名稱 PADI6 Rabbit pAb
中文名稱 蛋白質(zhì)精氨酸亞型6抗體
別    名 hPADVI; PADI6; PADI6_HUMAN; peptidyl arginine deiminase like protein; peptidyl arginine deiminase type VI; Peptidylarginine deiminase type 6; Peptidylarginine deiminase type VI; Peptidylarginine deiminase VI; protein arginine deiminase type 6; Protein arginine deiminase type VI; Protein-arginine deiminase type VI; Protein-arginine deiminase type-6.  
研究領(lǐng)域 發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 77 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PADI6: 101-200/694 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]

Function:
Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ovary, testis and peripheral blood leukocytes.

Similarity:
Belongs to the protein arginine deiminase family.

SWISS:
Q6TGC4

Gene ID:
353238

Database links:

Entrez Gene: 353238 Human

Omim: 610363 Human

SwissProt: Q6TGC4 Human

Unigene: 531598 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PADI6) Polyclonal Antibody, Unconjugated (bs-19703R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse placenta tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PADI6) Polyclonal Antibody, Unconjugated (bs-19703R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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