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P2Y1 Rabbit pAb (bs-23150R)  
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產品編號 bs-23150R
英文名稱 P2Y1 Rabbit pAb
中文名稱 P2Y1受體抗體/嘌呤受體抗體
別    名 ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor.  
研究領域 信號轉導  轉錄調節(jié)因子  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2Y1: 301-373/373 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]

Function:
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P47900

Gene ID:
5028

Database links:

Entrez Gene: 100135592 Guinea pig

Entrez Gene: 5028 Human

Entrez Gene: 18441 Mouse

Entrez Gene: 25265 Rat

Omim: 601167 Human

SwissProt: P59902 Guinea pig

SwissProt: P47900 Human

SwissProt: P49650 Mouse

SwissProt: P49651 Rat

Unigene: 654526 Human

Unigene: 281452 Mouse

Unigene: 10217 Rat



P2Y1 receptor 為離子通道蛋白,一種受體配體開啟的離子通道,介導細胞外核苷酸細胞間信號傳導。
產品圖片
Sample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Ovary tissue lysates Lane 3: Mouse Adrenal gland tissue lysates Primary: Anti-P2Y1 (bs-23150R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 55 kDa
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