| 產(chǎn)品編號 | V5209 |
| 英文名稱 | phospho-Tau (Thr181) Mouse mAb |
| 中文名稱 | 磷酸化微管相關(guān)蛋白單克隆抗體 |
| 別 名 | Tau (phospho T181); p-Tau (phospho T181); Tau(Phospho-Thr181); MAPT(phospho T181); p-Tau(Thr181); MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN. |
| 產(chǎn)品類型 | 磷酸化抗體 |
| 克 隆 號 | 5B2 |
| 理論分子量 | 46/79 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 純 度 | >90% as determined by SDS-PAGE |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. SWISS: P10636 Gene ID: 4137 Database links: Entrez Gene: 4137 Human Entrez Gene: 17762 Mouse Omim: 157140 Human SwissProt: P10636 Human SwissProt: P10637 Mouse Unigene: 101174 Human Unigene: 1287 Mouse Unigene: 2455 Rat |
