產(chǎn)品編號(hào) | V3311 |
英文名稱 | Human NT-proBNP Mouse mAb |
中文名稱 | 人腦納素前體蛋白單克隆抗體 |
別 名 | Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP. |
克 隆 號(hào) | 1e+11 |
理論分子量 | 8.5 kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
純 度 | >90% as determined by SDS-PAGE |
緩 沖 液 | 0.01M PBS(pH7.4). |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume.
The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing. SWISS: P16860 Gene ID: 4879 應(yīng)用推薦(Capture-Detection): V3305-V3306 |
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