| 產(chǎn)品編號(hào) | bsm-55545R |
| 英文名稱 | Myeloperoxidase Recombinant Rabbit mAb |
| 中文名稱 | 髓過(guò)氧化物酶重組兔單抗 |
| 別 名 | MPO, myeloperoxidase |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | SB135 |
| 交叉反應(yīng) | Mouse,Rat |
| 產(chǎn)品應(yīng)用 | IHC-P=1:200-800,IHC-F=1:200-800,IF=1:200-800
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Mouse MPO |
| 亞 型 | IgG |
| 純化方法 | Affinity Purification |
| 緩 沖 液 | PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol. |
| 保存條件 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. SWISS: P11247 Gene ID: 17523 髓過(guò)氧化物酶（MPO）是一種過(guò)氧化物酶，由17號(hào)染色體上的MPO基因編碼。MPO在中性粒細(xì)胞中表達(dá)得最多，并產(chǎn)生次氯酸以進(jìn)行抗菌活動(dòng)，其鈉鹽是漂白劑中的化學(xué)物質(zhì)。它是一種溶酶體蛋白，儲(chǔ)存在中性粒細(xì)胞的嗜氮顆粒中，并在脫顆粒時(shí)釋放到細(xì)胞外空間。MPO在急性骨髓性白血病、粒細(xì)胞性白血病、單核細(xì)胞性白血病、成髓細(xì)胞瘤和其它造血系統(tǒng)疾病的成髓細(xì)胞和未成熟骨髓細(xì)胞中表達(dá)，在某些肺癌和卵巢癌也可見(jiàn)表達(dá)。 |
