產(chǎn)品編號 | IHC0498R |
英文名稱 | Rat VDAC1 Ready-To-Use IHC Kit |
中文名稱 | 大鼠等電壓依賴性陰離子通道(內(nèi)參)即用型免疫組化試劑盒 |
別 名 | voltage dependent anion channel 1; AL033343; PORIN; VDAC; VDAC-1; VDAC1; Vdac5 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity. SWISS: P21796 Gene ID: 7416 |
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