產(chǎn)品編號(hào) | bs-6554R-Gold |
英文名稱 | Rabbit Anti-NOL8/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的核仁蛋白8抗體 |
別 名 | C9orf34; NOL8; NOL8_HUMAN; NOP132; Nucleolar protein 8; Nucleolar protein Nop132. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 腫瘤細(xì)胞生物標(biāo)志物 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 132kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NOL8 (841-885aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Summary: NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth Function: Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. Subunit: Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7. Interacts with DDX18; the interaction is RNA-dependent. Interacts with DDX47; the interaction is RNA-dependent. Subcellular Location: Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis. Tissue Specificity: Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. Post-translational modifications: Phosphorylated Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: Q76FK4.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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