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Rabbit Anti-NKG2A/Gold Conjugated antibody (bs-2411R-Gold)
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說(shuō) 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2411R-Gold
英文名稱 Rabbit Anti-NKG2A/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的NK細(xì)胞受體2A抗體
別    名 KLRC1; C lectin type II protein; CD159 antigen like family member A; CD159A; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2; NKG2A_HUMAN; NKG2-A/NKG2-B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2A.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse NKG2A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subunit:
Can form disulfide-bonded heterodimer with CD94.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 3821 Human

Entrez Gene: 16641 Mouse

Omim: 161555 Human

SwissProt: P26715 Human

Unigene: 512576 Human

Unigene: 56899 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

自然殺傷細(xì)胞活化性受體2A
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