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Rabbit Anti-C11ORF77/AP Conjugated antibody (bs-9934R-AP)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9934R-AP
英文名稱 Rabbit Anti-C11ORF77/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的11號染色體開放閱讀框77抗體
別    名 Chromosome 11 open reading frame 77; FLJ32675; HARB1_HUMAN; HARBI1; Harbinger transposase derived 1; Harbinger transposase-derived nuclease; Putative nuclease HARBI1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C11ORF77/HARBI1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
HARBI1 is a 349 amino acid nuclear and cytoplasmic protein belonging to the HARBI1 family. Members of the HARBI1 family of proteins are highly conserved in humans to various bony fish. Considered a transposase-derived protein, HARBI1 may possess nuclease activity and is expressed in brain, eye, nerve tissue, kidney and lung. HARBI1 utilizes divalent metal cations as cofactors, interacts with NAIF1 and promotes translocation to the nucleus. HARBI1 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

Subunit:
Interacts with NAIF1.

Subcellular Location:
Nucleus. Cytoplasm. Interaction with NAIF1 promotes translocation to the nucleus.

Tissue Specificity:
Detected in brain, eye, nerve tissue, kidney and lung.

Similarity:
Belongs to the HARBI1 family.

Database links:

Entrez Gene: 283254 Human

Entrez Gene: 241547 Mouse

Entrez Gene: 690164 Rat

SwissProt: Q96MB7 Human

SwissProt: Q8BR93 Mouse

SwissProt: B0BN95 Rat

Unigene: 714463 Human

Unigene: 130331 Mouse

Unigene: 198635 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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