產(chǎn)品編號 | bs-11060R-APC |
英文名稱 | Rabbit Anti-OTOA/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的耳聾、常染色體隱性遺傳22抗體 |
別 名 | Cancer/testis antigen 108; CT108; Deafness, autosomal recessive 22; DFNB22; OTOA; OTOAN_HUMAN; Otoancorin. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞外基質(zhì) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 122kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OTOA/DFNB22 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2. Function: May act as an adhesion molecule. Subcellular Location: Apical cell membrane. Secreted > extracellular space > extracellular matrix. At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes. DISEASE: Defects in OTOA are the cause of deafness autosomal recessive type 22 (DFNB22) [MIM:607039]. DFNB22 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Similarity: Belongs to the stereocilin family. Database links: Entrez Gene: 146183 Human Entrez Gene: 246190 Mouse Omim: 607038 Human SwissProt: Q7RTW8 Human SwissProt: Q8K561 Mouse Unigene: 408336 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 蜜桃一区二区在线视频 | 91大神人妻论坛性趣 | 国产农村新婚一级A片 | 国产精品成人无码a 无码 | 国产精品福利视频 | AⅤ 国产 美女 白丝 | 少妇婬荡视频在线播放 | 美女视频网站直接进入 | 日韩成人在线啊啊啊 | 熟妇少妇任你躁在线无码 | 极品少妇一区二区三区 | 国产又大又黄又粗视频 | 国产伦子伦一级A片免费看小说 | 天天AAA无码精品级 丝袜被扒在线观看网站 | 国产人成视频在线观看 | 天美传媒妇乱XXXXX视频 | 乱子伦熟妇aVvvzhe汁 | 无码少妇一级A片在线观看 9l视频自拍蝌蚪9l成人 | 亚洲熟妇人妻三级片网站 | AV偷拍破解夫妻偷拍片 | 日本亚洲精品码无专区 | av24小时国产在线播放 | 91在线观看视频免费 | 嫩BBB槡BBBB槡BBBB电影 | 美女黄色裸体视频网站 | 围产精品久久久久久久久久久久 | 午夜成人电影在线观看 | 黃色一级A片一毛片黄欢欢春雨 | 蜜桃av无码一区二区三区 | 91亚洲 欧美 国产 | 911亚洲精品无码成人A片在线 | 特级西西444www大胆高清图片 | 搡老女人老妇女aaa一区麻豆 | 91在线观看视频免费 | 国产精品福利一区二区三区四季 | 亚洲精品爆乳一区二区h | 一区二区三区中文字幕 | 波多野结衣国产区42部 | 电车痴汉五十路熟妇 | 久久久无码精品人妻一区蜜桃网站 |