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Rabbit Anti-DATF1/BF488 Conjugated antibody (bs-7659R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7659R-BF488
英文名稱 Rabbit Anti-DATF1/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的死亡相關(guān)轉(zhuǎn)錄因子1抗體
別    名 BYE 1; BYE1; C20orf158; DATF 1; Death associated transcription factor 1; Death inducer obliterator 1; DIDO 1; DIDO 2; DIDO 3; DIDO1; DIDO2; DIDO3; DIO 1; DIO1; hDido 1; hDido1; KIAA0333; DIDO1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 244kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DATF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Apoptosis plays an important role in many cellular processes. In mice, the death inducer obliterator 1 (Dio1) gene, a putative transcription factor, is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. Dio1 expression is upregulated when an apoptosis is detected. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. Human DATF1 (death associated transcription factor 1) is similar to the mouse gene and therefore is thought to be involved in apoptosis.

Function:
Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the indoleamine 2,3-dioxygenase family.

Database links:

Entrez Gene: 11083 Human

Entrez Gene: 23856 Mouse

Omim: 604140 Human

SwissProt: Q9BTC0 Human

SwissProt: Q8C9B9 Mouse

Unigene: 15783 Human

Unigene: 517172 Human

Unigene: 253836 Mouse

Unigene: 485484 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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