| 產(chǎn)品編號(hào) | bs-7672R-BF488 |
| 英文名稱 | Rabbit Anti-NRH2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的死亡結(jié)構(gòu)域蛋白NRH2抗體 |
| 別 名 | NRADD; PLAIDD; NRADD_RAT; Death domain-containing membrane protein NRADD; Neurotrophin receptor homolog-2; Neurotrophin receptor-alike death domain protein; P75-like apoptosis-inducing death domain protein. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Mouse, Rat, Dog, Pig, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat NRH2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: A single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. Function: Modulates NTRK1 signaling. Can activate severalintracellular signaling pathways, leading to activation of JUN.Promotes translocation of SORT1 to the cell membrane, and therebyhinders lysosomal degradation of SOTR1 and promotes its interactionwith NGFR (By similarity). Both isoform 1 and isoform 2 promoteapoptosis. Subunit: Interacts with NTRK1. Isoform 1 andisoform 2 interact with NGFR. Interacts with SORT1. Subcellular Location: Cell membrane; Single-pass type III membraneprotein. Nucleus (By similarity). Note=Proteolytic processing givesrise to an intracellular domain that translocates to the nucleus. Tissue Specificity: Detected in embryo, including embryonic brain.Detected at very low levels in adult testis, spleen, thymus andlung. Post-translational modifications: Isoform 1 is N-glycosylated. Isoform 2 is not N-glycosylated. Similarity: Contains 1 death domain. Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
