產(chǎn)品編號(hào) | bs-7895R-AP |
英文名稱 | Rabbit Anti-DBF4A/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的S期激酶活化蛋白DBF4A抗體 |
別 名 | Activator of S phase kinase; ASK; Chiffon homolog A; DBF4; DBF4 type zinc finger containing protein 1; DBF4-type zinc finger-containing protein 1; DBF4A; DBF4A_HUMAN; Protein DBF4 homolog A; ZDBF1. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 77kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DBF4A |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines. Function: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Subunit: Forms a complex with CDC7. Note that CDC7 forms distinct complex either with DBF4A or DBF4B. Such complexes are stable upon replication stress. Interacts with MEN1, MCM2, ORC2, ORC4 and ORC6. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 2 BRCT domains. Contains 1 DBF4-type zinc finger. Database links: UniProtKB/Swiss-Prot: Q9UBU7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 无码人妻一区二区三区蜜桃 | 黄网站免费在线观看 | 无套内谢少妇毛片A片流出白浆 | 日本一区二区三区久久 | 女女蕾丝边一区二区三区国产 | 四季AV一区二区三区免费观看 | 日韩无码一区二区不卡 | 成人A片潘金莲在线观看九色 | 久久久久久久久va豆产国 | 成人做爰69片免费看的注意事项 | 午夜精品久久久久久久99老熟妇 | 精品国产乱码久久久久久蜜柚 | 色情A片直播免费观看 | 精品国产乱码久久久久久1区2区-亚洲 | 久久国产精品人妻aⅴ | 一级片视频网站免费看 | 蜜桃AV鲁一鲁一鲁一鲁樱花影院 | 色欲av永久无码精品无码蜜桃 | 影音先锋最新av资源网 | 国内精品国产成人三级 | 久久国产精品一区二区 | 中文AV在线播放 | 奇米奇奇四色二区 | 7777k成人无码免费 | 少妇BBBBBB高潮A片 | 黄a无码片内射无码视频 | 国产裸体美女永久免费无遮挡 | 国产精品国产高清国产 | 熟女如虎的丰满熟妇啪啪 | 欧美搡BBBB搡BBB扫妇高潮 | 国产成人精品女人久久久 | 精品一二三四区在线电影 | 免费黄色视频在线观看一区二区 | 一本色道久久88综合亚洲精品Ⅰ | 女生被操的流白浆视频在线观看 | 成人在线一区二区 | 四川少妇BBBw搡BBBB搡BBBB | 裸体美女永久免费无遮挡 | 日本无码人妻波多野结衣杨思敏 | 亚洲AV无码乱码A片秀色直播 |