| 產(chǎn)品編號(hào) | bs-0887R-APC |
| 英文名稱 | Rabbit Anti-MV hemagglutinin glycoprotein/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的麻疹病毒血凝素抗體 |
| 別 名 | H protein; HA; H; Measles virus hemagglutinin; Hemagglutinin glycoprotein; HEMA_MEASE; MV HA. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)菌及病毒 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 68kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Measles virus hemagglutinin protein |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis. Subunit: Interacts with human PVRL4; this interaction allows virus infection of the respiratory epithelium (By similarity). Interacts with human MCP/CD46 antigen and SLAMF1. Subcellular Location: Virion membrane; Single-pass type II membrane protein (Potential). Host cell membrane; Single-pass type II membrane protein (By similarity). Similarity: Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily. Database links: UniProtKB/Swiss-Prot: P08362.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 麻疹病毒血凝素蛋白(Hemagglutinin protein,H)是介導(dǎo)麻疹病毒吸附、侵入宿主細(xì)胞的關(guān)鍵分子,麻疹病毒H蛋白在細(xì)胞膜上的表達(dá)，以及被麻疹病毒感染的細(xì)胞和未感染細(xì)胞的直接接觸能夠引起其受體CD46的表達(dá)下調(diào). |
