產(chǎn)品編號 | bs-1052R-Bio |
英文名稱 | Rabbit Anti-NAP1L1/Biotin Conjugated antibody |
中文名稱 | 生物素標(biāo)記的核小體組裝蛋白1抗體 |
別 名 | NAP1L; FLJ16112; hNRP; HSP22 like protein interacting protein; MGC23410; MGC8688; NAP 1; NAP 1 related protein; NAP 1L; NAP-1 related protein; NAP-1-related protein; NAP1; NAP1 L1; NAP1 related protein; Nap1l1; NAP1L1 protein; NP1L1_HUMAN; NRP; Nucleosome assembly protein 1 like 1; Nucleosome assembly protein 1-like 1. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 染色質(zhì)和核信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Rat, (predicted: Mouse, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 44kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NAP1L1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. The binding of sequence-specific DNA binding proteins to human nucleosome assembly protein 1 may be an important step contributing to the activation of transcription. May be involved in modulating chromatin formation and contribute to regulation of cell proliferation. Function: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation. Subcellular Location: Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Similarity: Belongs to the nucleosome assembly protein (NAP) family. Database links: Entrez Gene: 4673 Human Entrez Gene: 53605 Mouse Omim: 164060 Human SwissProt: P55209 Human SwissProt: P28656 Mouse Unigene: 524599 Human Unigene: 695185 Human Unigene: 290407 Mouse Unigene: 162938 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 核小體組裝蛋白1(NAP-1) 作為核心組蛋白的分子伴蛋白,在進化過程中是相當(dāng)保守的.它通過幫助核心組蛋白沉積到DNA上來促進核小體的組裝.而大量研究表明,酵母和動物中的NAP類似蛋白除了具有核小體組裝能力以外,還有其它多種功能 |
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