產(chǎn)品編號(hào) | bs-8328R-Gold |
英文名稱(chēng) | Rabbit Anti-PP4R3B/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的絲氨酸/蘇氨酸蛋白磷酸酶3B抗體 |
別 名 | Protein Phosphatase 4, Regulatory Subunit 3 Beta; smk1; FLFL2; PPP4R3B; PSY2; Serine/threonine-protein phosphatase 4 regulatory subunit 3B; SMEK 2; SMEK homolog 2; SMEK homolog 2 suppressor of mek1 (Dictyostelium); SMEK homolog 2 suppressor of mek1; FLJ31474; KIAA1387; PP4R3 beta; PP4R3B; PPP4R3 Beta; P4R3B_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 97kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SMEK2/PP4R3B |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol. Function: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Subunit: Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complex PPP4C-PPP4R2-PPP4R3B. Subcellular Location: Cytoplasm. Cytoskeleton. Centrosome. Nucleus. Note: In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions. Tissue Specificity: Moderately expressed in tissues and specific brain regions examined. Similarity: Belongs to the SMEK family. Contains 1 WH1 domain. Database links: UniProtKB/Swiss-Prot: Q5MIZ7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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