强伦轩一级A片在线观看,中文字幕乱码人妻二区三区,鲁鲁狠狠狠7777一区二区,西西4444www无码精品
掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
国产精品久久久久久亚洲影视 ,亚洲一区二区三区乱码在线观看,成年免费视频黄网站在线观看
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-SEMCAP3/Gold Conjugated antibody (bs-9191R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9191R-Gold
英文名稱 Rabbit Anti-SEMCAP3/Gold Conjugated antibody
中文名稱 膠體金標記的SEMCAP3蛋白抗體
別    名 Ligand of Numb protein X 3; likely ortholog of mouse semaF cytoplasmic domain associated protein 3; LNX3; PDZ domain containing ring finger 3; Protein SEMACAP3; SEMACAP3; Semaphorin cytoplasmic domain associated protein; PZRN3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  發(fā)育生物學  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 120kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEMCAP3/LNX3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
PDZRN3 contains a RING-finger motif in its N-terminal region, two PDZ domains in its central region and a consensus-binding motif for PDZ domains at its C-terminus. It was identified in silico as a homolog of the protein known as LNX1 or SEMCAP1, which possesses ubiquitin ligase activity and binds the membrane protein Semaphorin 4C. However, PDZRN3 itself has not previously been characterized. We have now evaluated the properties and functions of PDZRN3. The PDZRN3 gene was shown to be expressed in various human tissues including the heart, skeletal muscle and liver and its expression in mouse skeletal muscle was developmentally regulated. Both the differentiation of C2C12 mouse skeletal myoblasts into myotubes and injury-induced muscle regeneration in vivo were found to be accompanied by up-regulation of PDZRN3. The differentiation-associated increase in the expression of PDZRN3 in C2C12 cells follows that of myogenin and precedes that of myosin heavy chain. Depletion of PDZRN3 by RNA interference inhibited the formation of myotubes as well as the associated up-regulation of myosin heavy chain in C2C12 cells. Our data suggest that PDZRN3 plays an essential role in the differentiation of myoblasts into myotubes by acting either downstream or independently of myogenin.

Function:
E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity).

Subunit:
Interacts with NLGN1 and EFNB2 (By similarity). Interacts with UBE2D2 and with MUSK via the first PDZ domain (By similarity).

Tissue Specificity:
SEMCAP3 is widely expressed at high levels, and is thought to be involved in protein/zinc ion binding.

Post-translational modifications:
Auto-ubiquitinated (By similarity).

Similarity:
Contains 2 PDZ (DHR) domains.
Contains 1 RING-type zinc finger.
Contains 1 TRAF-type zinc finger.

Database links:

Entrez Gene: 23024 Human

Entrez Gene: 55983 Mouse

Entrez Gene: 312607 Rat

Omim: 609729 Human

SwissProt: Q9UPQ7 Human

SwissProt: Q69ZS0 Mouse

SwissProt: P68907 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 nmgps.com 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
一级A片色情大片视频我和少妇 | 伊人久久精品一区二区三区 | 精品人妻无码一区二区三区蜜桃一 | 国产一级A片久久久免费看快餐 | 四川寡妇XXXXXXXXX| 精品高潮呻吟久久av无码 | 亚洲无码专区一区二区 | 成人免费毛片 嘿嘿连载视频 | 国产无码手机在线观看 | 四川少妇搡BBB搡BBB搡多人伦 | 天天爱天天做天天大综合 | 性猛交乱婬AV毛片爽亚洲AV | 国产裸体美女免费无遮挡 | 国产一国产一级毛片视瓶 | 第一福利视频导航 | 海角 久久 大香蕉 | 国产精品伦子伦免费 | 免费观看婬片A片AAA毛片蜜唇 | A片男女色情A片免费姬媚直播 | 青青草原在线视频免费观看 | 色情网一区二区三区四区无码视频 | 人妻饥渴偷公乱中文字幕 | 99精品视频在线观看 | 97人人爽人人爽人人爽 | 国内精A片一二三区在线 | 亚洲VS高潮喷水久久双男男男 | 性感美女黄色视频免费网站 | 美女视频黄a视频全免费观看蜜臀 | 黄色毛片在线观看 | 欧美一性一乱一交一视频 | 三人成全免费观看电视剧高清完整版 | 中文字幕人妻无码精品一区二区 | 少妇的肉体AAAAA免费视频 | 少妇搡BBBB搡BBB搡视频一级 | 免费网站在线观看禁18进入 | 裸体无码人A片免费看 | 无码不卡AV毛片久久婷 | ..少妇泬出白浆狠狠躁夜夜躁 | 人人澡人人爱人人摸 | 江苏少妇性BBB搡BBB爽爽爽 | 四川BBB搡BB水多 |