| 產(chǎn)品編號 | bs-9197R-BF488 |
| 英文名稱 | Rabbit Anti-IGSF5/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的免疫球蛋白超家族成員5抗體 |
| 別 名 | GSF5; IgSF5; IGSF5_HUMAN; Immunoglobulin superfamily 5 like; Immunoglobulin superfamily member 5; JAM-4; Junctional adhesion molecule 4. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IGSF5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells. Function: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). Subunit: Interacts with MAGI1 at tight junctions, forms a tripartite complex with NPHS1 (By similarity). Interacts with LNX1 isoform 2 via its PDZ 2 domain, it may also interact with other isoforms containing this domain (By similarity). Subcellular Location: Cell membrane; Single-pass membrane protein (By similarity). Cell junction, tight junction (By similarity). Similarity: Belongs to the immunoglobulin superfamily. Contains 2 Ig-like V-type (immunoglobulin-like) domains. Database links: Entrez Gene: 150084 Human Omim: 610638 Human SwissProt: Q9NSI5 Human Unigene: 422120 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
