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Rabbit Anti-MYLPF/Gold Conjugated antibody (bs-5159R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-5159R-Gold
英文名稱(chēng) Rabbit Anti-MYLPF/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的快速骨骼肌肌球蛋白輕鏈2抗體
別    名 2410014J02Rik; DKFZp779C0757; DTNB; Fast skeletal myosin light chain 2; G2; HUMMLC2B; MGC13450; MLC 2; MRLC2; MYL11; MLC2B; MLC2F; MLRS_HUMAN; MYLPF; Myosin light polypeptide 2 alkali; Myosin regulatory light chain 2, skeletal muscle isoform.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fast skeletal myosin light chain 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins . Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.

Subunit:
Myosin is a hexamer of 2 heavy chains and 4 light chains.

Tissue Specificity:
Expressed in fetal and adult skeletal muscle.

Similarity:
Contains 3 EF-hand domains.

Database links:

Entrez Gene: 29895 Human

Entrez Gene: 396470 Chicken

Entrez Gene: 317657 Cow

Entrez Gene: 4632 Human

Entrez Gene: 17901 Mouse

Entrez Gene: 17907 Mouse

Entrez Gene: 24584 Rat

Entrez Gene: 56781 Rat

Omim: 160780 Human

SwissProt: P02609 Chicken

SwissProt: P05976 Human

SwissProt: P06741 Human

SwissProt: Q14324 Human

SwissProt: P05978 Mouse

SwissProt: P97457 Mouse

SwissProt: P02602 Rabbit

SwissProt: P02603 Rabbit

SwissProt: P02600 Rat

SwissProt: P04466 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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