產(chǎn)品編號(hào) | bs-4279R-AP |
英文名稱 | Rabbit Anti-Growth Arrest Specific Protein 7/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的生長(zhǎng)休止特定蛋白7抗體 |
別 名 | GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 54kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described. Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons. Subcellular Location: Cytoplasm (By similarity). DISEASE: Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. Similarity: Contains 1 FCH domain. Contains 1 SH3 domain. Contains 1 WW domain. Database links: Entrez Gene: 8522 Human Omim: 603127 Human SwissProt: O60861 Human Unigene: 258855 Human Unigene: 462214 Human Unigene: 17160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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