產品編號 | bs-2928R-BF350 |
英文名稱 | Rabbit Anti-PDLIM3/BF350 Conjugated antibody |
中文名稱 | BF350標記的輔肌動蛋白相關LIM蛋白抗體 |
別 名 | ALP; Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM-3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 細胞生物 免疫學 信號轉導 細胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
產品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 39kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PDLIM3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. Function: May play a role in the organization of actin filament arrays within muscle cells. Subunit: Interacts with ACTN2. Subcellular Location: Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines. Tissue Specificity: Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific. Similarity: Contains 1 LIM zinc-binding domain. Contains 1 PDZ (DHR) domain. Database links: Entrez Gene: 27295 Human Entrez Gene: 53318 Mouse Omim: 605889 Human SwissProt: Q53GG5 Human SwissProt: O70209 Mouse Unigene: 442702 Human Unigene: 731826 Human Unigene: 282900 Mouse Unigene: 13361 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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