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Rabbit Anti-PDLIM3/BF350 Conjugated antibody (bs-2928R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2928R-BF350
英文名稱 Rabbit Anti-PDLIM3/BF350 Conjugated antibody
中文名稱 BF350標記的輔肌動蛋白相關LIM蛋白抗體
別    名 ALP; Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM-3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDLIM3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

Function:
May play a role in the organization of actin filament arrays within muscle cells.

Subunit:
Interacts with ACTN2.

Subcellular Location:
Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.

Tissue Specificity:
Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific.

Similarity:
Contains 1 LIM zinc-binding domain.
Contains 1 PDZ (DHR) domain.

Database links:

Entrez Gene: 538516 Cow

Entrez Gene: 27295 Human

Entrez Gene: 53318 Mouse

Entrez Gene: 114108 Rat

Omim: 605889 Human

SwissProt: Q3SYZ8 Cow

SwissProt: Q53GG5 Human

SwissProt: O70209 Mouse

SwissProt: Q66HS7 Rat

Unigene: 442702 Human

Unigene: 731826 Human

Unigene: 282900 Mouse

Unigene: 13361 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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