產品編號 | bs-5912R-AP |
英文名稱 | Rabbit Anti-CYPA/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標記的親環(huán)蛋白(親環(huán)素)PPIA抗體 |
別 名 | Cyclophilin A; CyclophilinA; Cyclosporin A binding protein; Cyclosporin A-binding protein; CYPA; CYPH; Peptidyl prolyl cis trans isomerase A; Peptidyl-prolyl cis-trans isomerase A; Peptidylprolyl isomerase A; PPIA; PPIA protein; PPIA_HUMAN; PPIase A; Rotamase A; RotamaseA; T cell cyclophilin. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 免疫學 信號轉導 t-淋巴細胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Rabbit, ) |
產品應用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 18kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Cyclophilin A. |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity (1). Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins (2,3). Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans (4,5). CyPA is known for its involvement in T cell differentiation and proliferation and is highly expressed in brain (6). CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication (7,8). Cyclophilin B (CyPB) is a member of the cyclophilin family with specific N- and C-terminal extensions. Unlike CyPA, CyPB has a signal sequence leading to its translocation in the endoplasmic reticulum. CyPB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes (9,10). Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Subcellular Location: Cytoplasm. Similarity: Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. Contains 1 PPIase cyclophilin-type domain. Database links: Entrez Gene: 5478 Human Entrez Gene: 268373 Mouse Omim: 123840 Human SwissProt: P62937 Human SwissProt: P17742 Mouse Unigene: 356331 Human Unigene: 598115 Human Unigene: 5246 Mouse Unigene: 118772 Rat Unigene: 1463 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
| 国产丝袜在线熟女高潮 | 无码精品ThePorn| 全免费A级毛片免费看网站招嫖 | 少妇BBBBB精品大荫道 | 精品嫩草98AV在线观看 | 淫香淫色天天影视 | 中国大学生老师性服务黄色片一区二区 | 成人h动漫精品一区二区三区无码 | 一级A婬片试看60分钟 | 91久久精品无码视频 | 女人a级久久毛片 | 東北老熟女黃色A片 | 少妇人妻偷人精品无码 | 国产精品美女久久久久AV超清 | 搡老妇女一区二区三区四区 | 午夜国产精品秘 入口无码 国产成人无码综合亚洲日韩 | 一本大道之高清乱伦视频 | 亚洲涩情91日韩一区二区 | 欧美黑人猛插性爱视频 | 日日嗨aV一区二区三区 | 久久综合亚洲精品资源种子入口 | 无码人妻一区二区三区潮湿 | 日本少妇被强伦轩视频 | 国产无码在线观看黄 | 国产又粗又大又黄视频在线观看 | 一级特黄大片在线观看 | 四川少妇BBBB槡BBBB槡 | 日本高清人妻少妇视频免费观看 | 丰满人妻熟女aⅴ中文字幕 eeuss鲁丝片aⅴ无码 | 麻豆国产一区二区三区四区 | 敌伦交换一区二区三区 | 黑人狂躁日本艳妇A片软件下载 | 黄色同房视频免费观看 | 果冻传媒之漂亮人妻煮饭 | 直播级婬片A片免费播软件 欧美一级婬片A片免费软件 | 亚洲国产婷婷香蕉久久久久久99 | 国产成人视频一区二区 | 亚洲射色精品大地资源 | 国产精品久久久久久免费播放 | 午夜理理伦电影A片无码蜜桃av |