產(chǎn)品編號(hào) | bs-5954R-Gold |
英文名稱 | Rabbit Anti-RASA3/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的Ras-GTP酶激活蛋白3抗體 |
別 名 | GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; Ras GTPase activating protein 3; RAS p21 protein activator 3; RASA 3.RASA3_HUMAN |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 91kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RASA3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4). Function: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor. Subcellular Location: Cell membrane. Similarity: Contains 1 Btk-type zinc finger. Contains 2 C2 domains. Contains 1 PH domain. Contains 1 Ras-GAP domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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