產(chǎn)品編號 | bs-6121R-PE-Cy5 |
英文名稱 | Rabbit Anti-RBMX/hnRNP G/PE-Cy5 Conjugated antibody |
中文名稱 | PE-Cy5標(biāo)記的糖蛋白P43抗體 |
別 名 | hnRNP G; HNRPG; Glycoprotein p43; HNRPG; RNA binding motif protein, X chromosome; Heterogeneous nuclear ribonucleoprotein G; RBMX; RBMXP1; RBMXRT; RBMX_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號 糖蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Cow, Rabbit, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HNRPG |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Heterogeneous nuclear ribonuclearproteins (hnRNPs) are nucleic acid binding proteins and have critical roles in DNA repair, telomere regulation, and transcriptional gene regulation. hnRNP G has tumor suppressive activity and this RNA binding protein which may be involved in pre-mRNA splicing. Function: RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways; promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment. Subunit: Homomultimer. Interacts with SAFB/SAFB1 (By similarity). Found in the supraspliceosome complex. Identified in the spliceosome C complex. Interacts with KHDRBS3. Forms a complex with ILF2, ILF3, YLPM1, KHDRBS1, NCOA5 and PPP1CA. Interacts with CLK2, KHDRBS2, SAFB, TRA2B and YTHDC1. Interacts with ERAP1; the interaction is RNA-independent. Subcellular Location: Nucleus. Note=Component of ribonucleosomes. Localizes in numerous small granules in the nucleus. Tissue Specificity: Expressed strongly in oral keratinocytes, but only weakly detected in oral squamous cell carcinomas (at protein level). Post-translational modifications: O-glycosylated. Arg-185 is dimethylated, probably to asymmetric dimethylarginine. Cleavage of initiator Met is partial. If Met-1 is not removed, it is acetylated. If it is removed, Val-2 is acetylated. Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 27316 Human Entrez Gene: 19655 Mouse Omim: 300199 Human SwissProt: P38159 Human SwissProt: Q9WV02 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 黄色黄色黄色一级一级一级 | 东北女人无套内谢毛片 | 国产一级久久久久毛片精品 | 日本人妻一区二区三区 | 无码人妻一区二区三区香港经典 | 人人妻人人澡人人爽 | 77777人妻少妇毛片A片 | 亂倫近親相姦中文字幕网站 | 搡BBB搡BBB免费观看 | 无码粉嫩小泬抽搐白浆免费 | 亚洲欧美日韩综合 | 江苏少妇性BBB搡BBB爽爽爽 | 久久午夜无码鲁丝片午夜精品 | 无码AV一区二区三区黄台国产 | 美女美乳摸摸日日夜夜 | 初中麻豆啪啪啪黑丝免费 | 蜜桃 av 一区二区 | 337p粉嫩大胆色噜噜噜 | A片试看120分钟做受图片 | 中文字幕寂寞少妇 | 四川性BBB搡BBB爽爽爽小说 | 一区二区三区在线观看免费 | 爱爱动态图Chinese | 真正的免费毛片网站 | 日本三级视频在线观看 | 中文字幕日本被黑人无码 | 下面抽搐喷白浆高清无码啊啊啊 | 午夜无码精品一区二区三区99午 | 国产人妻无码一区二区三区不卡 | 亚洲欧美日韩丝袜自慰 | 真实的国产乱XXXX在线 | 2019中文在线观看免费观看电视剧 | 色婷婷五月一区二区三区 | 国产一级a毛一级a毛观看视频网站 | 特级西西www大胆无码 | 探花视频一区二区三区高清免费在线观看 | 国产肥白大熟妇BBBB视频 | 四川少妇BBBBBB爽爽爽欧美 | 黄色视频链接在线观看 | 又粗又大又黄A片免费看樱花 |