產(chǎn)品編號 | bs-14209R-BF488 |
英文名稱 | Rabbit Anti-DCXR/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的羰基還原酶2抗體 |
別 名 | Carbonyl reductase 2; Carbonyl reductase II; DCR; Dcxr; DCXR_HUMAN; Dicarbonyl L xylulose reductase; Dicarbonyl/ L xylulose reductase; Dicarbonyl/L-xylulose reductase; HCR2; HCRII; Human carbonyl reductase 2; kiDCR; Kidney dicarbonyl reductase; L xylulose reductase; L-xylulose reductase; P34H; SDR20C1; Short chain dehydrogenase/reductase family 20C member 1; Sperm surface protein P34H; XR. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DCXR |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: DCXR is a 244 amino acid member of the short-chain dehydrogenases/reductases family. This peripheral membrane protein catalyzes NADPH-dependent reduction of mulitple sugars, including L-xylulose, to the osmolyte xylitol. Producing xylitol in the renal tubules can prevent osmotic stress. L-xylulose reductase functions as a homotetramer and is expressed highly in kidney, liver and epididymis. Essential pentosuria is the result of a partial deficiency of L-xylulose reductase. Red blood cells of normal individuals contain two L-xylulose reductases: a major and a minor isozyme. Red cells from patients with pentosuria contain only one isozyme. Due to its role in the uronate cycle of glucose metabolism, L-xylulose reductase has been implicated in the management of the long term complications of diabetes. Function: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. Subcellular Location: Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol. Tissue Specificity: Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis. DISEASE: Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Database links: Entrez Gene: 51181 Human Entrez Gene: 67880 Mouse Omim: 608347 Human SwissProt: Q7Z4W1 Human SwissProt: Q91X52 Mouse Unigene: 9857 Human Unigene: 231091 Mouse Unigene: 177518 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 26uuu偷拍 亚洲 欧洲 综合 | 波多野结衣办公室人妻 | 17.c-起草国产免费永久网站 | 亚洲AV无码国产午夜 | 人妻多毛丰满熟妇av无码 | 国产成人无码精品久久久影院 | 蜜桃一区二区在线视频 | 精品无码人妻一区二区免费蜜桃 | 人妻无码аⅴ天堂中文在线 | 无套内谢的新婚少妇白浆 | 被两个男人躁我一个好爽 | 午夜呻吟一区二区三区 | 亚洲一区二区三区含羞草 | 特西西人体门四WW高清 | 精品国产三级A∨在线 | 国产在线啊啊啊要射了 | 91无码人妻精品1国产一区二区 | 亚洲天堂国产精品 | 亚洲国产精品二二三三区 | 欧美一区二区爽爽爽 | 日本强伦轩人妻一区二区 | 精品秘 无码一区二区久久 无码免费婬AV片在线观看 | 日本无码白浆一区二区 | 国产免费高清无码 | 9l人人澡人人妻人人精品 | 欧一美一色一伦一A片 | 久久久91精品国产一区苍井空 | 国产高清欧美性爱首页 | 国产精品jizz中国一级片 | 国产一级a毛一级a做免费高清视频 | 手机在线观看AV | 红桃视频网站一区二区精品 | 中文有码人妻熟女久久电影 | 国产免费一区二区三区 | 粗屌狠干骚穴内射 | 国产熟妇AV欧差aA片爽 | 欧洲美女自慰在线观看免费播放器 | 国产与黑人一级A片免费 | 国产无码电影在线观看 | 久久久久一区二区三区 |