| 產(chǎn)品編號(hào) | bs-19283R-APC |
| 英文名稱(chēng) | Rabbit Anti-NLRP11/APC Conjugated antibody |
| 中文名稱(chēng) | APC標(biāo)記的NLRP11蛋白抗體 |
| 別 名 | CLR19.6; FLJ26273; NACHT leucine rich repeat and PYD containing 11; NACHT LRR and PYD domains containing protein 11; NACHT, LRR and PYD domains-containing protein 11; NAL11_HUMAN; NALP11; NLR family pyrin domain containing 11; NLRP11; NOD17; Nucleotide binding oligomerization domain protein 17; Nucleotide-binding oligomerization domain protein 17; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD and NACHT containing protein 10B; PAAD and NACHT domain containing protein 10; PAAD-and NACHT domain-containing protein 10; PAN10; PYPAF6; PYPAF7; PYRIN containing APAF1 like protein 6; PYRIN-containing APAF1-like protein 6. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 118kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLRP11 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008] Function: Involved in inflammation. Similarity: Belongs to the NLRP family. Contains 1 DAPIN domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 NACHT domain. Database links: Entrez Gene: 204801 Human Omim: 609664 Human SwissProt: P59045 Human Unigene: 375039 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
