產(chǎn)品編號 | bs-16514R-RBITC |
英文名稱 | Rabbit Anti-ZNF687/RBITC Conjugated antibody |
中文名稱 | 羅丹明(RBITC)標(biāo)記的鋅指蛋白687抗體 |
別 名 | 4931408L03Rik; DKFZp781I1719; KIAA1441; mKIAA1441; RP11-126K1.3; Zfp687; Zinc finger protein 687; ZN687_HUMAN; ZNF687. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 129kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF687 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF687 (zinc finger protein 687) is a 1,237 amino acid nuclear protein that is involved in transcriptional regulation. A member of the Krüppel C2H2-type zinc-finger protein family, ZNF687 contains ten C2H2-type zinc fingers and exists as two alternatively spliced isoforms. The gene encoding ZNF687 maps to human chromosome 1, which comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 10 C2H2-type zinc fingers. Database links: Entrez Gene: 57592 Human Entrez Gene: 78266 Mouse Omim: 610568 Human SwissProt: Q8N1G0 Human SwissProt: Q9D2D7 Mouse Unigene: 186756 Human Unigene: 389478 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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