| 產(chǎn)品編號(hào) | bs-16745R-PE-Cy5 |
| 英文名稱(chēng) | Rabbit Anti-TRIM5 gamma/PE-Cy5 Conjugated antibody |
| 中文名稱(chēng) | PE-Cy5標(biāo)記的環(huán)指蛋白88抗體 |
| 別 名 | RING finger protein 88; RNF88; TRIM5; TRIM5_HUMAN; TRIM5alpha; Tripartite motif containing 5; Tripartite motif protein 5; Tripartite motif protein TRIM5; Tripartite motif-containing protein 5; Weakly similar to regulatory protein rpt 1 [M.musculus]. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRIM5 gamma |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Isoform Alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection. Targets retroviral capsid soon after entry into the cell, and prevents reverse transcription of the virus RNA genome. Isoform Alpha trimers may make multiple contacts with the hexameric lattice of CA proteins which constitute the surface of retrovirion core, and somehow inactivate the virus. Restricts efficiently infection by N-MLV, but not HIV-1. May have E3 ubiquitin-protein ligase activity. Subcellular Location: Cytoplasm > P-body. Cytoplasmic bodies. Post-translational modifications: Ubiquitinates itself in a RING finger- and UBE2D2-dependent manner (in vitro). Similarity: Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 85363 Human Omim: 608487 Human SwissProt: Q9C035 Human Unigene: 370515 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
