產(chǎn)品編號(hào) | bs-2088R-Gold |
英文名稱 | Rabbit Anti-Rabies virus Glycoprotein/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的狂犬病病毒糖蛋白抗體 |
別 名 | Rabies virus G; RV Glycoprotein; Rabies virus. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)菌及病毒 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 58kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from Rabies virus Glycoprotein |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
Function: Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Subunit: Homotrimer. Interacts with matrix protein. Subcellular Location: Virion membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Post-translational modifications: Glycosylated and palmitoylated by host. Glycosylation is crucial for glycoprotein export at the cell surface. {ECO:0000269|PubMed:1587845, ECO:0000269|PubMed:9451021}. Similarity: Belongs to the lyssavirus glycoprotein family. Database links: Entrez Gene: 1489856 Rabies virus Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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