產(chǎn)品編號(hào) | bsm-51134M-APC |
英文名稱 | Mouse Anti-GABARAP/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的小鼠抗γ-氨基丁酸受體相關(guān)蛋白單克隆抗體 |
別 名 | ATG8A; FLC 3B; FLC3B; FLJ25768; GABA(A) receptor associated protein; GABA(A) receptor-associated protein; GABARAP a; GABARAP; Gamma aminobutyric acid receptor associated protein; Gamma-aminobutyric acid receptor-associated protein; GBRAP_HUMAN; MGC120154; MGC120155; MM 46; MM46. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 G蛋白信號(hào) |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號(hào) | 10B2 |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Rabbit, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 14kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant human GABARAP protein |
亞 型 | IgG1 |
純化方法 | affinity purified by Protein G |
儲(chǔ) 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008] Function: May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Subunit: Interacts with GPHN and NSF. Interacts with GABRG2, beta-tubulin and ULK1. Interacts with CALR. Interacts with DDX47. Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25. Subcellular Location: Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules. Tissue Specificity: Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the MAP1 LC3 family. Database links: Entrez Gene: 11337 Human Entrez Gene: 56486 Mouse Omim: 605125 Human SwissProt: O95166 Human SwissProt: Q9DCD6 Mouse Unigene: 647421 Human Unigene: 272460 Mouse Unigene: 8411 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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